Radiophysics and MRI physics laboratory

Faculty of Medicine | Erasme Campus

(Code: ULB836)

Person in charge of the unit : REYNAERT Nick.

The research activities of our laboratory, combining clinical and fundamental research, are developed as part of multidisciplinary approaches and in close
collaboration with the departments of Nuclear Medicine, Radiology and Radiotherapy. Thanks to the different expertise of our researchers and our intrinsic
collaborations, our research topics are highly diversified.
One of our principal research fields concerns the development of data sciences, including
artificial intelligence techniques. Our goal is to develop predictive and prognostic models for internal and external radiotherapy treatments, and on a
broader level of Oncology treatments. Biomarkers are extracted from perfusion CT, functional MRI and metabolic/molecular (SPECT and PET) images using Radiomics
analysis, possibly combined with biomarkers coming from Genomics, Proteomics, etc. This research topic is of particular interest for the concomitant
development of the MRI-Linac and the Theranostic agents (e.g. 68-Gallium/177-Lutetium PRRT and PSMA, etc.). Optimal cancer care needs a holistic view of the
patient and the disease and the development of such predictive and prognostic models are deemed essential for improving patient selection and the guidance of
their treatment plan.
Another important aspect of our research is the optimization of radiotherapy techniques, notably using artificial intelligence for
automatic image delineation (CT, MRI and PET images), absorbed-dose prediction, generation of pseudo-CT from MRI images and TCP/NTCP modelling. This
research pillar also focuses on integrating multimodality imaging as part of precision radiotherapy approaches (MRI guided robotic brachytherapy, MRI guided
Gammaknife, Theranostics dosimetry, etc).
Moreover our laboratory has research projects in 3D printing, in radiobiology (collaborations with the BRTP:
Brussels RadioTheragnostic Platform and the PIRaTH: Preclinical imaging and radiation therapy platform) and on the combination of radiotherapy techniques with
immunotherapy. Last but not least, we are participating in the research activities of future proton therapy facilities in Charleroi.

Campus :	Campus Hospitalo-Fac
	Campus Erasme
Location :	Institut Jules Bordet, 4ème étage
Address :	CP610 - Meylemeersch, 90 - 1070 Anderlecht
Phone number :	+32 (0) 2 541 38 85
Fax :	+ 32 (0) 2 541 32 24
E-mail :	nick.reynaert@bordet.be
Web site :	https://www.bordet.be/fr/physique-medicale

Disciplines CRef :

• Cancerology

• Hygiene and nuclear medicine

• Medical imaging, radiology, tomography

• Radiobiology

• Sanitary and medical statistics

ULB Research ⤶	Description of the Unit	Projects of the Unit	Composition
Collaborations of the Unit	Protected technologies	Publications	Skills