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Ongoing teaching

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Units

Molecular Cell Physiology

Person in charge of the Unit : Oui

Our research mainly focuses on the yeast S. cerevisiae which is a paradigm model system for dissecting the molecular mechanisms of basic cellular functions in eukaryotes. A wide panel of methods are readily applicable to yeast, ranging from classical genetics and biochemistry to genomics and proteomics. Furthermore, basic cellular mechanisms are highly conserved from yeast to human. This is why some aspects of our work have now been extended to mammals as well.

Projetcs

Roles of ubiquitin and lipids in trafficking of membrane proteins

This project aims at elucidating the role of a small protein - named ubiquitin - and lipids in the intracellular trafficking and degradation of membrane proteins. For this, amino acid permeases of yeast are used as a model system.  

Study of a signalling pathway responding to external amino acids in yeast

This project aims at elucidating the molecular mechanisms of the signalling pathway activated by the yeast Ssy1 sensor in response to detection of external amino acids, in particular to understand the role of ubiquitin in this regulatory cascade.