Development of image analysis tools, notably involving Artificial Intelligence (machine learning and deep learning), for the
characterization of histopathological biomarkers via the extraction of new morphological, protein or genomic descriptors (based on IHC
or CISH). In addition to morphological aspects, these descriptors allow to describe staining heterogeneity (on whole slides) via
topological aspects (organization, spatial distribution, hot-spots) as well as the colocalization of biomarkers on whole slides and
TMA.