Faculty / Departement ⤶ |
Register by Units | Register by Projects | Register of researchers |
Register by Collaborations | Ranking by Domains | Ranking by Frascati | Disciplines CREF |
Units : High Resolution Nuclear Magnetic Resonance | ULB707
Photo-reactions of organometallic compounds are studied by NMR by illuminating the sample with a laser directly within the superconducting magnet of the spectrometer. The photo-reactions of certain Ru(II) complexes with biological targets (guanosine 5'-monophosphate, tyrosine, tryptophan) give rise to Chemically Induced Dynamic Nuclear Polarization: CIDNP. The (photo)-CIDNP originates from the hyperfine coupling within a pair of (photo-)chemically generated radicals which leads to a modification of the population distribution of nuclear spin states. In the NMR spectrum, reaction products are observed with signals whose intensity can be increased or decreased significantly compared to that observed at equilibrium (without illumination). Stationary CIDNP measures make possible, in particular, to identify the sites of photo-reaction and to characterize the radicals formed with the atomic resolution of NMR. They open up new perspectives for studying the photochemistry of Ru(II) or other transition metal complexes and for the characterization of biological (macro)molecules. The work is carried out in collaboration with the teams of C. Moucheron - A. Kirsch and N. Vaeck.
Web site: http://cop.ulb.ac.be
• F.R.S.-FNRS et Fonds associés (hors FRIA)
• Fonds associés (toutes subventions, y compris la Loterie Nat.)
• Financement de base institutionnel
• Fonds propres (patrimoine)