Stem cells (SCs) have the unique capacity to self-renew and to differentiate into the cell lineages that constitute their tissue
of origin.  SCs are found in many adult tissues, including skin epidermis. SCs are critical for replenishing and maintaining the
balance of cells (homeostasis) within the tissue, and for regenerating tissue damaged during injury. Study of SCs opens new
therapeutic avenues for degenerative diseases and cancer. Several kinds of cancer harbour cells with characteristics typical of SCs,
including high capacity for self-renewal and ability to reform a tumour after transplantation. Our group is studying the role of SC
from an onclogic perspective (skin and breast tumors) and in embryonic development of the heart.