The quantitative interpretation of biological data requires the use of computer assisted approaches. A first approach consists of
the statistical analysis of data in order to support relevance and significance of biological observations. A second approach
deals with the elaboration and the computer simulation of models in order to test the validity of intuitively proposed schemas of
regulation pathways. Theoretical studies have been especially conducted in the field of second messenger-controlled cascades (cyclic
AMP, InsP3 , Ca2+) and receptor activation (TSH receptor, InsP3-receptor-Ca2+-channel).